Our Doctors, Embryologists and staff through ALPHA IVF & the other fertility centres we worked with, produced numerous 1sts:
- Invented a womb mimicking machine called “SHOOGLE” that aims to improve circulation of nutrients to embryos.
- Demonstrated the importance of embryo transfer duration on pregnancy outcome. (14th World Congress on IVF and 3rd World Congress on IVM. Montreal, Canada. 15-19 September 2007)
- Demonstrated the value of tube rinsing in oocyte recovery procedure. (14th World Congress on IVF and 3rd World Congress on IVM. Montreal, Canada. 15-19 September 2007)
- Demonstrated a mathematical formula to guide doctors on appropriate quantum of ovarian drilling. (Life, Issue 9, Page 14-16, 2007)
- Reported delivery following the salvage of a presumably abnormal embryo. (7th Congress of PGDIS. Melbourne, Australia 13-15 June 2007)
- Demonstrated that an older uterus (about 40 years old) achieves similar pregnancy rates compared to uterus less than 30 years old. (Reproductive Biomedicine Online, 16(SUPPI2):S37-38 2008)
- PRP treatment for Ashermann’s Syndrome with resulting successful pregnancy and delivery. (2010)
- Successful pregnancy and delivery following PGD-CGH diagnosis of chromosome inversion with fresh transfer. (11th International Conference on PGD, May 17th – 19th 2012, Austria)
- Successful pregnancy and delivery in a patient with Mullerian Dysgenesis (a woman born without a vagina). (Reproductive BioMedicine Online, Vol 24, Issue 5, Pages 547-549), (May 2012)
- Reported successful pregnancy following the use of freeze-thawed sperm, freeze-thawed eggs, and freeze-thawed embryoes. (10th Royal College of O&G International Scientific Congress, June 2012)
- Demonstrated similar euploidy rates among D3 apronuclear (0PN), unipronuclear (1PN) and 2 PN embryos using MaCGH analysis. (12th International Conference on PGD. Istanbul, Turkey, May 2013)
- Demonstrated that embryos derived from conventional IVF have lower aneuploidy rates compared to embryos derived from ICSI. (13th International Conference on PGD. Cantebury, UK, May 2014)
- Successful live birth following frozen embryo transfer of a 1PN embryo after PGD-MaCGH analysis. (14th International Conference on PGD, Chicago, USA 2015)
- Demonstrated that combining a Day 5 and a Day 6 Blastocyst results in very high pregnancy rates (Clinical Pregnancy Rate: 71.4%, Implantation Rate: 46.4%). (6th Congress of the Asia Pacific Initiative on Reproduction, Jakarta, Indonesia, 8 – 10th April 2016)
- Demonstrated that administration of Clotrimazole prior to Frozen Embryo Transfer (FET) Cycles May Improve Implantation Rate. (16th International Conference on Preimplantation Genetic Diagnostic, Valencia, Spain, 2017)
- Successful live birth using high-resolution HLA (Human Leukocyte Antigen) genotyping from a single PGT biopsy in Savior Sibling Programme from a monogenic (62nd All India Congress of Obstetrics & Gynaecology (AICOG), Bengaluru, India, 8-12 Jan 2019)
- Demonstrated that repeated vitrification and repeated warming procedures have no detrimental effect on blastocyst survival and pregnancy outcome. (18th International Conference on Preimplantation Genetic Diagnosis, Geneva, Switzerland, 2019)
- Demonstrated that blastocysts arising from Day1-MII oocytes have the same euploidy rate as Day 0-MII oocytes from the same cycle and therefore should not be discarded. This will increase the number of euploid blastocysts available for embryo transfer. (9th Congress of Asia Pacific Initiative on Reproductive (ASPIRE), 3-5 May 2019. Central, Hong Kong)
- Successful live birth of a healthy baby following PGT for a couple in which both husband and wife were heterozygous for c.3365C>T and c.2280C>A mutations in the TBCD gene.
- Asia & Australia’s 1st successful pregnancy following world’s only proven sperm sorting technology after PGD-MaCGH analysis. (2015)
- Asia & Australia’s 1st successful pregnancy following world’s only proven sperm sorting technology after Intracytoplasmic Sperm Injection (ICSI). (2015)
- Asia & Australia’s 1st successful pregnancy following PGD-CGH diagnosis of chromosome translocation. (10th Royal College of O&G International Scientific Congress June 2012)
- Asia & Australia’s 1st pregnancies and babies through Micro-Array Comparative Genomic Hybridisation PGD for 24 chromosomes with fresh transfer. (2011)
- South East Asia’s 1st to achieve 100% survival for frozen blastocysts (2013)
- South East Asia’s 1st to achieve 100% survival for frozen embryos (2013)
- South East Asia’s 1st IVF Surrogate Baby (1995)
- South East Asia’s 1st to achieve successful pregnancy using artificial intelligence (AI)-enhanced embryo selection technology (March,2021)
- Malaysia & Singapore’s 1st PGD-PCR pregnancy for Alpha Thalassemia (2009)
- Malaysia & Singapore’s 1st In-Vitro Maturation (IVM) pregnancy (2008)
- Malaysia & Singapore’s 1st PGD for chromosomal translocation (2008)
- Malaysia & Singapore’s 1st vitrified-warmed blastocyst PGD pregnancy (2008)
- Malaysia & Singapore’s 1st Frozen embryo PGD baby (2006)
- Malaysia & Singapore’s 1st sequential transfer PGD pregnancies (Day 3 and Day 6) (2006)
- Malaysia & Singapore’s 1st PGD twins (2005)
- Malaysia & Singapore’s 1st blastocyst biopsied PGD baby (2005)
- Malaysia & Singapore’s 1st pregnancy following PGD (2004)
- Malaysia’s 1st successful pregnancy for Alpha Thalassemia using PGD with concurrent PGS on a single platform from a single biopsy (2015)
- Malaysia’s 1st Rescue-ICSI twin babies (2009)
- Malaysia’s 1st conception quadruplets (2 babies born each time 1.5 years apart) (2003)
- Malaysia’s 1st freeze-thaw blastocyst transfer pregnancy (2003)
- Malaysia’s 1st blastocyst transfer IVF baby (2002)
- Malaysia’s 1st sperm donor blastocyst transfer IVF baby (2002)
- Malaysia’s 1st blastocyst transfer ICSI baby (2002)
- Malaysia’s 1st Mesa-ICSI blastocyst transfer baby (2002)
- Malaysia’s 1st donated frozen embryo pregnancy (1999)
- Malaysia’s 1st conception twins born 1.5 years apart (1997)
- Malaysia’s 1st frozen embryo baby (1996)
- Malaysia’s 1st successful TEST (Tubal Embryo Transfer)(1989)
- Malaysia’s 1st successful PROST (Pronuclear Transfer) baby (1988)
- Malaysia’s 1st successful GIFT twins (1987)
- Malaysia’s 1st IVF Baby delivered (1986)
- Demonstrated successful twin pregnancy following transfer of a 2PN and 0PN embryo after PGD-MaCGH analysis. (ASRM, Baltimore, USA, 2015)
- Demonstrated that 1PN embryos can be normal & therefore should not be discarded. (14th International Conference on PGDIS, Chicago, USA, 2015)
- Demonstrated the safety of fertilization without ICSI for embryos undergoing PGS. (13th PGDIS 2014, Canterbury, UK)
- Achieved Malaysia’s highest IVF clinical pregnancy and take-home baby rates
- Produced the highest number of test-tube babies born in Malaysia
- Pioneered the successful application of Comparative Genomic Hybridisation for testing embryos with chromosomal inversion and translocation. (11th International Conference on PGD, 2012, Austria & 10th Royal College of O&G International Scientific Congress, 2012)
- Achieved Malaysia’s highest GIFT clinical pregnancy and take-home baby rates
- Developed a mathematical formula to guide doctors on appropriate quantum of ovarian drilling. (Life, Issue 9, Page 14-16, 2007)
- Demonstrated the value of tube rinsing in oocyte recovery procedure. (14th World Congress on IVF & 3rd World Congress on IVM. Montreal, Canada, 2007)
- Demonstrate the importance of embryo transfer duration on pregnancy outcome. (14th World Congress on IVF and 3rd World Congress on IVM. Montreal, Canada, 2007)
- Demonstrated that 0PN embryos can be normal & therefore should not be discarded. (7th Congress of PGDIS. Melbourne, Australia, 2007)
- Developed a highly-effective technique protocol and communication system for embryo transfer. (ASRM, 2005)
- Produced 11 consecutive ART pregnancies – obtained higher IVF pregnancy rates compared to all 67 IVF centres in the UK (2001)
- Invented a womb mimicking machine called “SHOOGLE” (Patent pending)
ALL THE ABOVE ARE ACHIEVED BY DOCTORS, EMBRYOLOGISTS, AND STAFF THAT NOW CONSTITUTE ALPHA IVF & WOMEN’S SPECIALISTS
